TABLE 2.Fast and slow inactivating components of 4-AP–sensitive Ka currents in control and CCD neurons
|
|
||
| Control | CCD | |
|
|
||
| Ifast (pA/pF) | 53.0 ± 6.8 | 30.4 ± 4.3* |
| τfast (ms) | 12.89 ± 2.12 | 10.46 ± 1.28 |
| Islow (pA/pF) | 16.3 ± 3.9 | 16.7 ± 3.2 |
| τslow (ms) | 130.7 ± 21.5 | 91.3 ± 9.8 |
| n | 15 | 15 |
Values are mean ± SE A two-term exponential function was used to fit the falling phase of 4-AP–sensitive Ka currents. The current amplitude (Ifast and Islow) and time constant (τfast and τslow) for each cell were determined.
* P < 0.01 (Student's t-test; significant difference between control and CCD).