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Article: Alterations in GABA(A) receptor mediated inhibition in adjacent dorsal midline thalamic nuclei in a rat model of chronic limbic epilepsy.

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Rajasekaran K; Kapur J; Bertram EH
J. Neurophysiol., 2007


TABLE 3.

Changes in IPSC frequency and amplitude in neurons of mediodorsal (MD) and paraventricular (PV) thalamus of control and epileptic animals after addition of 3 μM TTX

Nucleus/Group (n = Cells/Animals) Frequency, Hz Amplitude, pA
sIPSC mIPSC sIPSC mIPSC
Control MD (6/4) 0.28 ± 0.04 0.21 ± 0.04** 70.63 ± 8.68 77.54 ± 17.44
Epilepsy MD (7/4) 0.21 ± 0.04 0.16 ± 0.04* 67.49 ± 5.72 68.32 ± 3.97
Control PV (7/5) 0.29 ± 0.07 0.20 ± 0.05* 73.72 ± 7.24 66.76 ± 4.94
Epilepsy PV (8/6) 1.28 ± 0.33 0.80 ± 0.20* 99.71 ± 10.50 93.66 ± 8.20

  • Values are means±SE.

  • ↵* P < 0.05 compared to sIPSC;

  • ↵** P < 0.01 compared to sIPSC (paired t-test).


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Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source