TABLE 2.Comparison of values for action potential amplitude and duration between action potentials elicited from depolarizing steps and action potentials generated off of low-threshold spikes
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AP Induced by Depolarizing Step
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First AP on LTS
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Second AP on LTS
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Third AP on LTS
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Amplitude (mV) | 62.8 ± 0.8 (50-73) | 64.4 ± 0.9 (55-75) | 48.6 ± 2.2 (16-61)*† | 45.8 ± 3.0 (26-65)*† |
Duration (ms)
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1.3 ± 0.04 (0.8-2.7)
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1.1 ± 0.03 (0.8-1.4)
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1.4 ± 0.05 (0.8-2.1)*
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1.7 ± 0.08 (1.2-2.2)*†‡ |
Values are ± SE with range in parentheses. One-way ANOVA followed by Tukey's multiple comparison test: * statistically significant difference vs. 1st AP on the LTS (P < 0.01); † statistically significant difference vs. AP induced by depolarizing step (P < 0.001); ‡ statistically significant difference vs. 2nd AP on LTS (P < 0.05).