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Article: Dual mechanisms of angiotensin-induced activation of mouse sympathetic neurones.

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Ma X; Bielefeldt K; Tan ZY; Whiteis CA; Snitsarev V; Abboud FM; Chapleau MW
J. Physiol. (Lond.), 2006


Table 1. Peak IA currents, cell capacitance, time to peak IA (TTP), and time constant of IA current decay before and during Ang II in both tonic and phasic neurones

Control Ang II
Tonic (n = 7) Phasic (n = 6) Tonic (n = 5) Phasic (n = 5)
*Significant difference between phasic and tonic neurones (P < 0.05). †Significant difference between Ang II and control responses (P < 0.05). Data are expressed as means ± s.e.m.
Peak Current (pA) 1012 ± 63  466 ± 91*  756 ± 162† 370 ± 128
Capacitance (pF) 29 ± 6 31 ± 5   29 ± 6   31 ± 5 
TTP (ms)   2.4 ± 0.11 2.4 ± 0.07 2.5 ± 0.04 2.6 ± 0.2
τ (ms)   1.2 ± 0.07 1.3 ± 0.03 1.2 ± 0.04  1.2 ± 0.05

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Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
DRG IA cell membrane time constant (ms) 1.2 ± 0.07 1.2 (ms) Data Table
DRG IA cell cell capacitance (pF) 29.0 ± 6.0 29.0 (pF) Data Table