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Article: Local circuit properties underlying cortical reorganization.

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Hickmott PW; Merzenich MM
J. Neurophysiol., 2002


Table 1.

Intrinsic properties of neurons after various durations of denervation

Control Normal Acute 7 Day 14 Day 28 Day
Resting potential, mV −68.0 ± 1.1 (12) −70.6 ± 1.1 (25) −70.1 ± 1.1 (27) −72.4 ± 1.2 (29) −73.4 ± 1.2 (32) −72.3 ± 1.1 (31)
Input resistance, MΩ 122.0 ± 6.4 (11) 117.5 ± 4.1 (25) 97.8 ± 5.8*  (27) 91.4 ± 6.0*  (29) 97.7 ± 6.3*  (32) 99.6 ± 3.7*  (31)
  • Values are means ± SE with number of neurons in parentheses. Control, data from neurons close to the normal border in nondenervated animals (from Hickmott and Merzenich 1998); normal, data from neurons close to a nonborder site in nondenervated animals (from Hickmott and Merzenich 1998); and acute, 7 day, 14 day, and 28 day; data from neurons close to the normal or reorganized border sites after the indicated duration of denervation.

  • *  Significantly different from control value, P < 0.05.

  •  Significantly different from normal value, P < 0.05.


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Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Spinal cord ventral horn motor neuron alpha resting membrane potential (mV) -68.0 ± 1.1 (12) -68.0 (mV) Data Table
Spinal cord ventral horn motor neuron alpha input resistance (MΩ) 122.0 ± 6.4 (11) 122.0 (MΩ) Data Table