Table 2.
Comparison between RS and FS cells in previous studies
| Study | % Difference in Maximum Rate of Repolarization* | % Difference in Half-Width† | % Difference in fAHP‡ | Temperature |
|---|---|---|---|---|
| McCormick et al. (1985) | 70% | 150% | NA | 35–37°C |
| Massengill et al. (1997) | NA | 37% | 108% | Room |
| Cauli et al. (1997) | NA | 80% | 38% | Room |
| Erisir et al. (1999) | 73% | 183% | 99% | Room |
| Baranyi et al. (1993) | 28% | 64% | 55% | Physiological |
| Huettner and Baughman (1988) | 49% | 100% | NA | 30°C |
| Kawaguchi and Kubota (1998) | NA | 78% | NA | 30°C |
| Average | 55% | 99% | 75% | |
| Massengill et al. (1997), 100 μM 4-AP | NA | 86% | 88% | Room |
| Erisir et al. (1999), 1 mM TEA | 58% | 81% | NA | Room |
| Kv3.1−/− | 5% | −7% | 16% | Room |
| Kv3.1−/− | 30% | 21% | 9% | 34°C |
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RS, regular spiking; FS, fast spiking; fAHP, fast afterhyperpolarization; 4-AP, 4-aminopyridine; TEA, tetraethylammonium; NA, not available in the cited study.
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↵* % Difference in maximum rate of repolarization = (FS rate − RS rate)/FS rate.
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↵† % Difference in half-width = (RS half-width − FS half-width)/FS half-width.
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↵‡ % Difference in fAHP = (FS fAHP − RS fAHP)/FS AHP.