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Article: Elevated postsynaptic [Ca2+]i and L-type calcium channel activity in aged hippocampal neurons: relationship to impaired synaptic plasticity.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Thibault O; Hadley R; Landfield PW
J. Neurosci., 2001

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Hippocampus CA1 pyramidal cell input resistance (MΩ) 58.9 ± 3.7 (15) 58.9 (MΩ) Data Table
Hippocampus CA1 pyramidal cell input resistance (MΩ) 61.9 ± 3.3 (16) 61.9 (MΩ) Data Table
Hippocampus CA1 pyramidal cell resting membrane potential (mV) -58.7 ± 1.1 (15) -58.7 (mV) Data Table
Hippocampus CA1 pyramidal cell resting membrane potential (mV) -58.8 ± 1.3 (16) -58.8 (mV) Data Table
Hippocampus CA1 pyramidal cell rheobase (μA) 151.0 ± 15.0 (15) -- Data Table
Hippocampus CA1 pyramidal cell rheobase (μA) 181.0 ± 15.0 (16) -- Data Table
Hippocampus CA1 pyramidal cell spike amplitude (mV) 81.9 ± 2.3 (16) 81.9 (mV) Data Table
Hippocampus CA1 pyramidal cell spike amplitude (mV) 83.8 ± 1.3 (15) 83.8 (mV) Data Table
Hippocampus CA1 pyramidal cell spike width (msec) 2.4 ± 0.1 (16) 2.4 (ms) Data Table
Hippocampus CA1 pyramidal cell spike width (msec) 2.3 ± 0.2 (15) 2.3 (ms) Data Table

Report miscurated data

Metadata values

Experimental condition Value
RecTemp 21.0 - 23.0
AnimalAge 90.0 - 810.0
Strain Fischer 344
PrepType in vitro
Species Rats
ExternalSolution 5.0
JxnPotential Unreported
InternalSolution 5.0
ElectrodeType Sharp
internal_0_K 2000.0
internal_0_HEPES 40.0
external_0_Mg 2.0
external_0_Na 154.0
external_0_K 4.25
external_0_Cl 139.0
external_0_Ca 2.0
external_0_glucose 10.0

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
2956 Elevated postsynaptic [Ca2+]i and L-type calcium channel activity in aged hippocampal neurons: relationship to impaired synaptic plasticity. Thibault O; Hadley R; Landfield PW J. Neurosci. 2001 False 5 Shreejoy Tripathy, Brenna Li, Ryan Sefidpour, Dawson Born, 5
2957 Elevated postsynaptic [Ca2+]i and L-type calcium channel activity in aged hippocampal neurons: relationship to impaired synaptic plasticity. Thibault O; Hadley R; Landfield PW J. Neurosci. 2001 False 1 Shreejoy Tripathy, 1