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Article: Dopamine modulation of excitatory currents in the striatum is dictated by the expression of D1 or D2 receptors and modified by endocannabinoids.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
André VM; Cepeda C; Cummings DM; Jocoy EL; Fisher YE; William Yang X; Levine MS
Eur. J. Neurosci., 2010

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Neostriatum medium spiny neuron dorsal striatum medium-sized spiny D2 receptor-expressing neuron cell capacitance (pF) 85.8 ± 2.1 (69) 85.8 (pF) Data Table
Neostriatum medium spiny neuron dorsal striatum medium-sized spiny D1 receptor-expressing neuron cell capacitance (pF) 92.6 ± 2.4 (79) 92.6 (pF) Data Table
Neostriatum medium spiny neuron dorsal striatum medium-sized spiny D1 receptor-expressing neuron input resistance 76.0 ± 6.0 (79) 76.0 (MΩ) Data Table
Neostriatum medium spiny neuron dorsal striatum medium-sized spiny D2 receptor-expressing neuron input resistance 133.0 ± 12.0 (69) 133.0 (MΩ) Data Table
Neostriatum medium spiny neuron dorsal striatum medium-sized spiny D2 receptor-expressing neuron membrane time constant (ms) 2.2 ± 0.1 (69) 2.2 (ms) Data Table
Neostriatum medium spiny neuron dorsal striatum medium-sized spiny D1 receptor-expressing neuron membrane time constant (ms) 2.6 ± 0.1 (79) 2.6 (ms) Data Table

Report miscurated data

Metadata values

Experimental condition Value
Species Mice
ElectrodeType Patch-clamp
PrepType in vitro
ExternalSolution 5.0
InternalSolution 5.0
external_1_pH 7.4
external_1_Mg 2.0
external_1_Ca 0.1
external_1_Na 140.0
external_1_Cl 6.2
external_1_K 2.0
internal_1_pH 7.25
internal_1_Mg 2.0
internal_1_Na 4.4
internal_1_Cl 4.0
external_2_pH 7.4
external_2_Ca 2.0
external_2_Na 135.0
external_2_Cl 173.01
Strain Other
JxnPotential Unreported
AnimalAge 44.7 - 49.5
Strain Mouse, Transgenic
RecTemp 22.0
internal_0_pH 7.275
internal_0_Mg 6.0
internal_0_Na 24.0
internal_0_GTP 0.5
internal_0_ATP 5.0
internal_0_EGTA 5.0
internal_0_HEPES 10.0
internal_0_Cl 16.0
internal_0_Cs 140.0
external_0_pH 7.3
external_0_Mg 2.0
external_0_Na 157.25
external_0_K 3.0
external_0_Cl 141.0
external_0_Ca 2.0
external_0_glucose 10.0

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
15695 Dopamine modulation of excitatory currents in the striatum is dictated by the expression of D1 or D2 receptors and modified by endocannabinoids. André VM; Cepeda C; Cummings DM; Jocoy EL; Fisher YE; William Yang X; Levine MS Eur. J. Neurosci. 2010 False 4 Shreejoy Tripathy, Kerrie Tsigounis, 1