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Article: Normal electrical properties of hippocampal neurons modelling early Huntington disease pathogenesis.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Shelbourne P; Coote E; Dadak S; Cobb SR
Brain Res., 2007

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Hippocampus CA1 pyramidal cell adaptation ratio (1st) 20.75 (7) -- Data Table
Hippocampus CA1 pyramidal cell adaptation ratio (1st) 22.91 (15) -- Data Table
Hippocampus CA1 pyramidal cell AHP amplitude (mV) 1.76 (15) 1.76 (mV) Data Table
Hippocampus CA1 pyramidal cell AHP amplitude (mV) 3.12 (7) 3.12 (mV) Data Table
Hippocampus CA1 pyramidal cell input resistance (MΩ) 108.1 (7) 108.1 (MΩ) Data Table
Hippocampus CA1 pyramidal cell input resistance (MΩ) 131.0 (15) 131.0 (MΩ) Data Table
Hippocampus CA1 pyramidal cell membrane time constant (ms) 20.62 (15) 20.62 (ms) Data Table
Hippocampus CA1 pyramidal cell membrane time constant (ms) 15.14 (7) 15.14 (ms) Data Table
Hippocampus CA1 pyramidal cell other (ms) 16.85 (15) 16.85 (None) Data Table
Hippocampus CA1 pyramidal cell other (ms) 6.15 (7) 6.15 (None) Data Table
Hippocampus CA1 pyramidal cell resting membrane potential (mV) -69.9 (7) -69.9 (mV) Data Table
Hippocampus CA1 pyramidal cell resting membrane potential (mV) -73.0 (15) -73.0 (mV) Data Table
Hippocampus CA1 pyramidal cell rheobase (nA) 0.05 (15) 50.0 (pA) Data Table
Hippocampus CA1 pyramidal cell rheobase (nA) 0.04 (7) 40.0 (pA) Data Table
Hippocampus CA1 pyramidal cell spike amplitude (mV) 65.9 (7) 65.9 (mV) Data Table
Hippocampus CA1 pyramidal cell spike amplitude (mV) 73.86 (15) 73.86 (mV) Data Table
Hippocampus CA1 pyramidal cell spike half-width (ms) 1.707 (15) 1.707 (ms) Data Table
Hippocampus CA1 pyramidal cell spike half-width (ms) 2.11 (7) 2.11 (ms) Data Table
Hippocampus CA1 pyramidal cell spike max decay slope (mV/ms) -45.6 (15) 45.6 (mV/ms) Data Table
Hippocampus CA1 pyramidal cell spike max decay slope (mV/ms) -43.6 (7) 43.6 (mV/ms) Data Table
Hippocampus CA1 pyramidal cell spike max rise slope (mV/ms) 109.0 (15) 109.0 (mV/ms) Data Table
Hippocampus CA1 pyramidal cell spike max rise slope (mV/ms) 100.7 (7) 100.7 (mV/ms) Data Table
Hippocampus CA1 pyramidal cell spike threshold (mV) -46.8 (15) -46.8 (mV) Data Table
Hippocampus CA1 pyramidal cell spike threshold (mV) -48.8 (7) -48.8 (mV) Data Table

Report miscurated data

Metadata values

Experimental condition Value
Species Mice
ElectrodeType Patch-clamp
PrepType in vitro
Strain Mouse, Transgenic
ExternalSolution 5.0
JxnPotential Unreported
InternalSolution 5.0
RecTemp 20.0 - 24.0
internal_0_Mg 4.0
internal_0_Na 9.3
internal_0_K 140.0
internal_0_GTP 0.3
internal_0_ATP 3.0
internal_0_EGTA 0.2
internal_0_HEPES 10.0
internal_0_Cl 28.5
external_0_Mg 7.0
external_0_Na 150.25
external_0_K 2.5
external_0_Cl 127.5
external_0_Ca 0.5
external_0_glucose 25.0

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
22662 Normal electrical properties of hippocampal neurons modelling early Huntington disease pathogenesis. Shelbourne P; Coote E; Dadak S; Cobb SR Brain Res. 2007 True 12 Shreejoy Tripathy, James liu, Athanasios Kritharis, 3