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Article: Hyperexcitability of cultured spinal motoneurons from presymptomatic ALS mice.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Kuo JJ; Schonewille M; Siddique T; Schults AN; Fu R; Bär PR; Anelli R; Heckman CJ; Kroese AB
J. Neurophysiol., 2004

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Spinal cord intermediate horn motor neuron sympathetic AHP amplitude 0.6 ± 0.3 (23) 0.6 (mV) Data Table
Spinal cord intermediate horn motor neuron sympathetic AHP amplitude (mV) 10.0 ± 2.0 (23) 10.0 (mV) Data Table
Spinal cord intermediate horn motor neuron sympathetic cell diameter 32.0 ± 6.0 (23) 32.0 (um) Data Table
Spinal cord intermediate horn motor neuron sympathetic FI slope 0.25 ± 0.12 (23) 0.25 (Hz/nA) Data Table
Spinal cord intermediate horn motor neuron sympathetic input resistance (MΩ) 52.0 ± 18.0 (23) 52.0 (MΩ) Data Table
Spinal cord intermediate horn motor neuron sympathetic resting membrane potential (mV) -52.0 ± 11.0 (23) -52.0 (mV) Data Table
Spinal cord intermediate horn motor neuron sympathetic rheobase (pA) 770.0 ± 640.0 (23) 770.0 (pA) Data Table
Spinal cord intermediate horn motor neuron sympathetic spike amplitude (mV) 77.0 ± 14.0 (23) 77.0 (mV) Data Table
Spinal cord intermediate horn motor neuron sympathetic spike threshold (mV) -45.0 ± 10.0 (23) -45.0 (mV) Data Table
Spinal cord intermediate horn motor neuron sympathetic spike width (ms) 2.5 ± 1.0 (23) 2.5 (ms) Data Table

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Metadata values

Experimental condition Value
Species Mice
Strain BALB C
ElectrodeType Patch-clamp
PrepType in vitro
JxnPotential Unreported
RecTemp 20.0 - 24.0
InternalSolution 5.0
ExternalSolution 5.0
PrepType cell culture
internal_0_K 75.0
internal_0_Cl 75.0
external_0_pH 7.4
external_0_Mg 1.3
external_0_Na 147.0
external_0_K 3.1
external_0_Cl 133.7
external_0_Ca 2.4
external_0_glucose 10.0

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
771 Hyperexcitability of cultured spinal motoneurons from presymptomatic ALS mice. Kuo JJ; Schonewille M; Siddique T; Schults AN; Fu R; Bär PR; Anelli R; Heckman CJ; Kroese AB J. Neurophysiol. 2004 False 10 Shreejoy Tripathy, Brenna Li, 2