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Article: Stimulation of D1-type dopamine receptors enhances excitability in prefrontal cortical pyramidal neurons in a state-dependent manner.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Lavin A; Grace AA Neuroscience, 2001
Inferred neuron-electrophysiology data values
| Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
|---|---|---|---|---|---|
| Neocortex pyramidal cell layer 5-6 | Prefrontal cortex layer 5-6 pyramidal neuron | AHP amplitude (mV) | 12.0 ± 8.4 | 12.0 (mV) | Data Table |
| Neocortex pyramidal cell layer 5-6 | Prefrontal cortex layer 5-6 pyramidal neuron | input resistance (MΩ) | 47.1 ± 16.9 | 47.1 (MΩ) | Data Table |
| Neocortex pyramidal cell layer 5-6 | Prefrontal cortex layer 5-6 pyramidal neuron | resting membrane potential (mV) | 74.2 ± 8.3 | -74.2 (mV) | Data Table |
| Neocortex pyramidal cell layer 5-6 | Prefrontal cortex layer 5-6 pyramidal neuron | rheobase (pA) | 50.0 ± 38.0 | 50.0 (pA) | Data Table |
| Neocortex pyramidal cell layer 5-6 | Prefrontal cortex layer 5-6 pyramidal neuron | spike amplitude (mV) | 56.4 ± 5.6 | 56.4 (mV) | Data Table |
| Neocortex pyramidal cell layer 5-6 | Prefrontal cortex layer 5-6 pyramidal neuron | spike threshold (mV) | 48.6 ± 7.0 | -48.6 (mV) | Data Table |
Metadata values
| Experimental condition | Value |
|---|---|
| Species | Rats |
| Strain | Rats, Sprague-Dawley |
| ExternalSolution | 5.0 |
| InternalSolution | 5.0 |
| PrepType | in vitro |
| RecTemp | 20.0 - 24.0 |
| ElectrodeType | Patch-clamp |
| JxnPotential | Corrected |
| AnimalAge | 14.0 - 21.0 |
| internal_0_pH | 7.3 |
| internal_0_Mg | 2.0 |
| internal_0_Na | 32.0 |
| internal_0_K | 140.5 |
| internal_0_GTP | 0.3 |
| internal_0_ATP | 3.0 |
| internal_0_EGTA | 0.02 |
| internal_0_HEPES | 10.0 |
| internal_0_Cl | 15.1 |
| external_0_Mg | 1.3 |
| external_0_Na | 150.0 |
| external_0_K | 6.2 |
| external_0_Cl | 133.8 |
| external_0_Ca | 2.4 |
| external_0_glucose | 10.0 |
Data table listing
| Data Table | Article Title | Authors | Journal | Year | Table needs expert? | Ephys table mentions | Curated by | Times validated |
|---|---|---|---|---|---|---|---|---|
| 47696 | Stimulation of D1-type dopamine receptors enhances excitability in prefrontal cortical pyramidal neurons in a state-dependent manner. | Lavin A; Grace AA | Neuroscience | 2001 | False | 6 | Shreejoy Tripathy, Nathalie Binnion, Brenna Li, | 2 |
| 47697 | Stimulation of D1-type dopamine receptors enhances excitability in prefrontal cortical pyramidal neurons in a state-dependent manner. | Lavin A; Grace AA | Neuroscience | 2001 | False | 6 | 0 | |
| 47698 | Stimulation of D1-type dopamine receptors enhances excitability in prefrontal cortical pyramidal neurons in a state-dependent manner. | Lavin A; Grace AA | Neuroscience | 2001 | False | 4 | 0 | |
| 47699 | Stimulation of D1-type dopamine receptors enhances excitability in prefrontal cortical pyramidal neurons in a state-dependent manner. | Lavin A; Grace AA | Neuroscience | 2001 | False | 4 | 0 |