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Article: Strychnine-sensitive glycine receptors on pyramidal neurons in layers II/III of the mouse prefrontal cortex are tonically activated.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Salling MC; Harrison NL
J. Neurophysiol., 2014

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Neocortex pyramidal cell layer 2-3 medial prefrontal cortex prelimbic area layers 2-3 pyramidal neuron ADP amplitude (mV) 3.2 ± 0.4 (30) 3.2 (mV) Data Table
Neocortex pyramidal cell layer 2-3 medial prefrontal cortex prelimbic area layers 2-3 pyramidal neuron cell capacitance (pF) 176.0 ± 7.0 (30) 176.0 (pF) Data Table
Neocortex pyramidal cell layer 2-3 medial prefrontal cortex prelimbic area layers 2-3 pyramidal neuron input resistance (MΩ) 156.0 ± 9.0 (30) 156.0 (MΩ) Data Table
Neocortex pyramidal cell layer 2-3 medial prefrontal cortex prelimbic area layers 2-3 pyramidal neuron membrane time constant (ms) 28.0 ± 2.0 (30) 28.0 (ms) Data Table
Neocortex pyramidal cell layer 2-3 medial prefrontal cortex prelimbic area layers 2-3 pyramidal neuron resting membrane potential (mV) -67.9 ± 1.0 (30) -67.9 (mV) Data Table
Neocortex pyramidal cell layer 2-3 medial prefrontal cortex prelimbic area layers 2-3 pyramidal neuron rheobase (pA) 111.0 ± 10.0 (30) 111.0 (pA) Data Table
Neocortex pyramidal cell layer 2-3 medial prefrontal cortex prelimbic area layers 2-3 pyramidal neuron sag amplitude (mV) 2.7 ± 0.4 (30) 2.7 (mV) Data Table
Neocortex pyramidal cell layer 5-6 medial prefrontal cortex prelimbic area layers 5-6 pyramidal neuron ADP amplitude (mV) 3.5 ± 0.4 (30) 3.5 (mV) Data Table
Neocortex pyramidal cell layer 5-6 medial prefrontal cortex prelimbic area layers 5-6 pyramidal neuron cell capacitance (pF) 170.0 ± 13.0 (30) 170.0 (pF) Data Table
Neocortex pyramidal cell layer 5-6 medial prefrontal cortex prelimbic area layers 5-6 pyramidal neuron input resistance (MΩ) 102.0 ± 9.0 (30) 102.0 (MΩ) Data Table
Neocortex pyramidal cell layer 5-6 medial prefrontal cortex prelimbic area layers 5-6 pyramidal neuron membrane time constant (ms) 16.0 ± 1.0 (30) 16.0 (ms) Data Table
Neocortex pyramidal cell layer 5-6 medial prefrontal cortex prelimbic area layers 5-6 pyramidal neuron resting membrane potential (mV) -69.5 ± 1.0 (30) -69.5 (mV) Data Table
Neocortex pyramidal cell layer 5-6 medial prefrontal cortex prelimbic area layers 5-6 pyramidal neuron rheobase (pA) 155.0 ± 14.0 (30) 155.0 (pA) Data Table
Neocortex pyramidal cell layer 5-6 medial prefrontal cortex prelimbic area layers 5-6 pyramidal neuron sag amplitude (mV) 4.0 ± 0.5 (30) 4.0 (mV) Data Table

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Metadata values

Experimental condition Value
Species Mice
ElectrodeType Patch-clamp
Strain Mice, Inbred C57BL
RecTemp 22.0 - 25.0
PrepType in vitro
InternalSolution 5.0
internal_1_Mg 3.0
internal_1_Na 4.3
internal_1_Cl 146.0
ExternalSolution 5.0
JxnPotential Unreported
AnimalAge 25.0 - 50.0
internal_0_Mg 2.0
internal_0_Na 5.3
internal_0_K 132.0
internal_0_GTP 0.3
internal_0_ATP 2.0
internal_0_EGTA 0.2
internal_0_HEPES 10.0
internal_0_Cl 9.0
external_0_Mg 2.0
external_0_Na 151.25
external_0_K 2.5
external_0_Cl 130.5
external_0_Ca 2.0
external_0_glucose 10.0

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
49594 Strychnine-sensitive glycine receptors on pyramidal neurons in layers II/III of the mouse prefrontal cortex are tonically activated. Salling MC; Harrison NL J. Neurophysiol. 2014 False 7 Kerrie Tsigounis, Ryan Sefidpour, 1
49595 Strychnine-sensitive glycine receptors on pyramidal neurons in layers II/III of the mouse prefrontal cortex are tonically activated. Salling MC; Harrison NL J. Neurophysiol. 2014 False 1 0