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Article: Intrinsic electrophysiology of mouse corticospinal neurons: a class-specific triad of spike-related properties.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Suter BA; Migliore M; Shepherd GM
Cereb. Cortex, 2013

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5b corticostriatal pyramidal neuron adaptation ratio (last/first ISI) 1.7 ± 0.25 (10) 1.7 (ratio) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5b corticospinal thick-tufted large pyramidal neuron adaptation ratio (last/first ISI) 0.88 ± 0.2 (10) 0.88 (ratio) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5b corticospinal thick-tufted large pyramidal neuron adaptation ratio (last/first ISI) 0.87 ± 0.24 (23) 0.87 (ratio) Data Table
Neocortex pyramidal cell layer 5-6 Secondary somatosensory cortex layer 5b corticospinal thick-tufted large pyramidal neuron adaptation ratio (last/first ISI) 0.77 ± 0.11 (7) 0.77 (ratio) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5b corticospinal thick-tufted large pyramidal neuron adaptation ratio (last/first ISI) 1.03 ± 0.34 (9) 1.03 (ratio) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5b corticospinal thick-tufted large pyramidal neuron FI slope (Hz/nA) 86.0 ± 24.0 (9) 86.0 (Hz/nA) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5b corticostriatal pyramidal neuron FI slope (Hz/nA) 61.0 ± 21.0 (10) 61.0 (Hz/nA) Data Table
Neocortex pyramidal cell layer 5-6 Secondary somatosensory cortex layer 5b corticospinal thick-tufted large pyramidal neuron FI slope (Hz/nA) 110.0 ± 23.0 (7) 110.0 (Hz/nA) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5b corticospinal thick-tufted large pyramidal neuron FI slope (Hz/nA) 115.0 ± 29.0 (10) 115.0 (Hz/nA) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5b corticospinal thick-tufted large pyramidal neuron FI slope (Hz/nA) 98.0 ± 18.0 (23) 98.0 (Hz/nA) Data Table
Neocortex pyramidal cell layer 5-6 Secondary somatosensory cortex layer 5b corticospinal thick-tufted large pyramidal neuron input resistance (MΩ) 47.1 ± 11.1 (7) 47.1 (MΩ) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5b corticospinal thick-tufted large pyramidal neuron input resistance (MΩ) 35.7 ± 7.6 (10) 35.7 (MΩ) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5b corticospinal thick-tufted large pyramidal neuron input resistance (MΩ) 42.7 ± 13.2 (23) 42.7 (MΩ) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5b corticospinal thick-tufted large pyramidal neuron input resistance (MΩ) 39.2 ± 12.6 (9) 39.2 (MΩ) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5b corticostriatal pyramidal neuron input resistance (MΩ) 90.6 ± 13.4 (10) 90.6 (MΩ) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5b corticospinal thick-tufted large pyramidal neuron resting membrane potential (mV) -82.7 ± 2.5 (23) -82.7 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5b corticostriatal pyramidal neuron resting membrane potential (mV) -84.3 ± 3.8 (10) -84.3 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5b corticospinal thick-tufted large pyramidal neuron resting membrane potential (mV) -81.6 ± 4.4 (9) -81.6 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Secondary somatosensory cortex layer 5b corticospinal thick-tufted large pyramidal neuron resting membrane potential (mV) -83.6 ± 3.9 (7) -83.6 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5b corticospinal thick-tufted large pyramidal neuron resting membrane potential (mV) -85.4 ± 3.2 (10) -85.4 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5b corticospinal thick-tufted large pyramidal neuron rheobase (pA) 330.0 ± 76.0 (9) 330.0 (pA) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5b corticostriatal pyramidal neuron rheobase (pA) 182.0 ± 73.0 (10) 182.0 (pA) Data Table
Neocortex pyramidal cell layer 5-6 Secondary somatosensory cortex layer 5b corticospinal thick-tufted large pyramidal neuron rheobase (pA) 286.0 ± 57.0 (7) 286.0 (pA) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5b corticospinal thick-tufted large pyramidal neuron rheobase (pA) 361.0 ± 87.0 (10) 361.0 (pA) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5b corticospinal thick-tufted large pyramidal neuron rheobase (pA) 341.0 ± 86.0 (23) 341.0 (pA) Data Table
Neocortex pyramidal cell layer 5-6 Secondary somatosensory cortex layer 5b corticospinal thick-tufted large pyramidal neuron sag ratio 18.5 ± 4.6 (7) 0.185 (ratio) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5b corticospinal thick-tufted large pyramidal neuron sag ratio 20.0 ± 3.6 (10) 0.2 (ratio) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5b corticospinal thick-tufted large pyramidal neuron sag ratio 21.0 ± 6.6 (23) 0.21 (ratio) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5b corticospinal thick-tufted large pyramidal neuron sag ratio 19.0 ± 6.0 (9) 0.19 (ratio) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5b corticostriatal pyramidal neuron sag ratio 6.7 ± 4.8 (10) 0.067 (ratio) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5b corticostriatal pyramidal neuron spike amplitude (mV) 65.6 ± 6.0 (10) 65.6 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Secondary somatosensory cortex layer 5b corticospinal thick-tufted large pyramidal neuron spike amplitude (mV) 85.7 ± 4.8 (7) 85.7 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5b corticospinal thick-tufted large pyramidal neuron spike amplitude (mV) 81.7 ± 3.2 (10) 81.7 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5b corticospinal thick-tufted large pyramidal neuron spike amplitude (mV) 75.8 ± 7.9 (23) 75.8 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5b corticospinal thick-tufted large pyramidal neuron spike amplitude (mV) 85.6 ± 6.9 (9) 85.6 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5b corticostriatal pyramidal neuron spike half-width (ms) 1.04 ± 0.25 (10) 1.04 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Secondary somatosensory cortex layer 5b corticospinal thick-tufted large pyramidal neuron spike half-width (ms) 0.61 ± 0.03 (7) 0.61 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5b corticospinal thick-tufted large pyramidal neuron spike half-width (ms) 0.51 ± 0.03 (10) 0.51 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5b corticospinal thick-tufted large pyramidal neuron spike half-width (ms) 0.65 ± 0.13 (23) 0.65 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5b corticospinal thick-tufted large pyramidal neuron spike half-width (ms) 0.59 ± 0.06 (9) 0.59 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5b corticospinal thick-tufted large pyramidal neuron spike max decay slope (mV/ms) -134.0 ± 33.0 (23) 134.0 (mV/ms) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5b corticospinal thick-tufted large pyramidal neuron spike max decay slope (mV/ms) -153.0 ± 23.0 (9) 153.0 (mV/ms) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5b corticostriatal pyramidal neuron spike max decay slope (mV/ms) -66.0 ± 19.0 (10) 66.0 (mV/ms) Data Table
Neocortex pyramidal cell layer 5-6 Secondary somatosensory cortex layer 5b corticospinal thick-tufted large pyramidal neuron spike max decay slope (mV/ms) -147.0 ± 15.0 (7) 147.0 (mV/ms) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5b corticospinal thick-tufted large pyramidal neuron spike max decay slope (mV/ms) -175.0 ± 10.0 (10) 175.0 (mV/ms) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5b corticospinal thick-tufted large pyramidal neuron spike max rise slope (mV/ms) 492.0 ± 95.0 (9) 492.0 (mV/ms) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5b corticostriatal pyramidal neuron spike max rise slope (mV/ms) 250.0 ± 68.0 (10) 250.0 (mV/ms) Data Table
Neocortex pyramidal cell layer 5-6 Secondary somatosensory cortex layer 5b corticospinal thick-tufted large pyramidal neuron spike max rise slope (mV/ms) 488.0 ± 45.0 (7) 488.0 (mV/ms) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5b corticospinal thick-tufted large pyramidal neuron spike max rise slope (mV/ms) 498.0 ± 55.0 (10) 498.0 (mV/ms) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5b corticospinal thick-tufted large pyramidal neuron spike max rise slope (mV/ms) 400.0 ± 91.0 (23) 400.0 (mV/ms) Data Table
Neocortex pyramidal cell layer 5-6 Secondary somatosensory cortex layer 5b corticospinal thick-tufted large pyramidal neuron spike peak (mV) 32.2 ± 3.3 (7) 32.2 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5b corticospinal thick-tufted large pyramidal neuron spike peak (mV) 25.9 ± 3.5 (10) 25.9 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5b corticospinal thick-tufted large pyramidal neuron spike peak (mV) 23.6 ± 6.5 (23) 23.6 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5b corticospinal thick-tufted large pyramidal neuron spike peak (mV) 30.2 ± 3.7 (9) 30.2 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5b corticostriatal pyramidal neuron spike peak (mV) 20.1 ± 5.3 (10) 20.1 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5b corticospinal thick-tufted large pyramidal neuron spike threshold (mV) -55.8 ± 3.0 (10) -55.8 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5b corticospinal thick-tufted large pyramidal neuron spike threshold (mV) -52.3 ± 3.0 (23) -52.3 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5b corticospinal thick-tufted large pyramidal neuron spike threshold (mV) -55.4 ± 4.8 (9) -55.4 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Primary motor cortex layer 5b corticostriatal pyramidal neuron spike threshold (mV) -45.6 ± 3.0 (10) -45.6 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Secondary somatosensory cortex layer 5b corticospinal thick-tufted large pyramidal neuron spike threshold (mV) -53.7 ± 3.0 (7) -53.7 (mV) Data Table

Report miscurated data

Metadata values

Experimental condition Value
Species Mice
ElectrodeType Patch-clamp
PrepType in vitro
AnimalAge 42.0 - 110.0
JxnPotential Corrected
InternalSolution 5.0
ExternalSolution 5.0
Strain C57BL
RecTemp 34.0
JxnOffset -10.5
internal_0_pH 7.3
internal_0_Mg 4.0
internal_0_Na 28.4
internal_0_K 130.0
internal_0_EGTA 1.0
internal_0_Cl 8.0
external_0_Mg 1.0
external_0_Na 153.25
external_0_K 2.5
external_0_Cl 135.5
external_0_Ca 5.0
external_0_glucose 25.0
external_0_gabazine 10.0
external_0_CPP 5.0
external_0_NBQX 10.0

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
36261 Intrinsic electrophysiology of mouse corticospinal neurons: a class-specific triad of spike-related properties. Suter BA; Migliore M; Shepherd GM Cereb. Cortex 2013 False 12 Shreejoy Tripathy, Athanasios Kritharis, Kerrie Tsigounis, Patrick Savage, Ellie Hogan, 4