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Article: Mice lacking the transcriptional coactivator PGC-1α exhibit alterations in inhibitory synaptic transmission in the motor cortex.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Dougherty SE; Bartley AF; Lucas EK; Hablitz JJ; Dobrunz LE; Cowell RM Neuroscience, 2014
Inferred neuron-electrophysiology data values
| Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
|---|---|---|---|---|---|
| Neocortex basket cell | Motor cortex layer 5 non fast spiking parvalbumin positive interneurons | AHP amplitude (mV) | 19.87 (2) | 19.87 (mV) | Data Table |
| Neocortex basket cell | Motor cortex layer 5 fast spiking parvalbumin positive interneurons | AHP amplitude (mV) | 17.41 (8) | 17.41 (mV) | Data Table |
| Neocortex basket cell | Motor cortex layer 5 non fast spiking parvalbumin positive interneurons | input resistance (MΩ) | 200.0 (2) | 200.0 (MΩ) | Data Table |
| Neocortex basket cell | Motor cortex layer 5 fast spiking parvalbumin positive interneurons | input resistance (MΩ) | 160.13 (8) | 160.13 (MΩ) | Data Table |
| Neocortex basket cell | Motor cortex layer 5 fast spiking parvalbumin positive interneurons | maximum firing rate (Hz) | 327.98 (8) | 327.98 (Hz) | Data Table |
| Neocortex basket cell | Motor cortex layer 5 non fast spiking parvalbumin positive interneurons | maximum firing rate (Hz) | 185.37 (2) | 185.37 (Hz) | Data Table |
| Neocortex basket cell | Motor cortex layer 5 fast spiking parvalbumin positive interneurons | resting membrane potential (mV) | -56.0 (8) | -56.0 (mV) | Data Table |
| Neocortex basket cell | Motor cortex layer 5 non fast spiking parvalbumin positive interneurons | resting membrane potential (mV) | -56.0 (2) | -56.0 (mV) | Data Table |
| Neocortex basket cell | Motor cortex layer 5 fast spiking parvalbumin positive interneurons | spike amplitude (mV) | 54.27 (8) | 54.27 (mV) | Data Table |
| Neocortex basket cell | Motor cortex layer 5 non fast spiking parvalbumin positive interneurons | spike amplitude (mV) | 64.6 (2) | 64.6 (mV) | Data Table |
| Neocortex basket cell | Motor cortex layer 5 fast spiking parvalbumin positive interneurons | spike half-width (ms) | 0.51 (8) | 0.51 (ms) | Data Table |
| Neocortex basket cell | Motor cortex layer 5 non fast spiking parvalbumin positive interneurons | spike half-width (ms) | 0.69 (2) | 0.69 (ms) | Data Table |
| Neocortex basket cell | Motor cortex layer 5 fast spiking parvalbumin positive interneurons | spike threshold (mV) | -43.63 (8) | -43.63 (mV) | Data Table |
| Neocortex basket cell | Motor cortex layer 5 non fast spiking parvalbumin positive interneurons | spike threshold (mV) | -43.04 (2) | -43.04 (mV) | Data Table |
Metadata values
| Experimental condition | Value |
|---|---|
| ElectrodeType | Patch-clamp |
| AnimalAge | 27.0 - 33.0 |
| ExternalSolution | 5.0 |
| InternalSolution | 5.0 |
| external_1_Mg | 1.0 |
| external_1_Ca | 2.0 |
| external_1_Na | 153.25 |
| external_1_Cl | 135.0 |
| external_1_K | 3.0 |
| internal_1_Na | 13.0 |
| internal_1_Cl | 9.0 |
| internal_1_K | 156.0 |
| Species | Mice |
| Strain | G42 |
| PrepType | in vitro |
| JxnPotential | Unreported |
| RecTemp | 22.0 |
| internal_0_pH | 7.2 |
| internal_0_Mg | 2.0 |
| internal_0_GTP | 0.2 |
| internal_0_ATP | 2.0 |
| internal_0_EGTA | 10.0 |
| internal_0_HEPES | 10.0 |
| internal_0_Cl | 129.0 |
| internal_0_Cs | 129.0 |
| external_0_Mg | 2.0 |
| external_0_Na | 151.0 |
| external_0_K | 3.5 |
| external_0_Cl | 136.5 |
| external_0_Ca | 2.0 |
| external_0_glucose | 10.0 |
Data table listing
| Data Table | Article Title | Authors | Journal | Year | Table needs expert? | Ephys table mentions | Curated by | Times validated |
|---|---|---|---|---|---|---|---|---|
| 47636 | Mice lacking the transcriptional coactivator PGC-1α exhibit alterations in inhibitory synaptic transmission in the motor cortex. | Dougherty SE; Bartley AF; Lucas EK; Hablitz JJ; Dobrunz LE; Cowell RM | Neuroscience | 2014 | False | 7 | Shreejoy Tripathy, Nathalie Binnion, | 2 |