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Article: Postsynaptic cell type-dependent cholinergic regulation of GABAergic synaptic transmission in rat insular cortex.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Yamamoto K; Koyanagi Y; Koshikawa N; Kobayashi M
J. Neurophysiol., 2010


Table 1.

Intrinsic electrophysiological properties of layer V interneurons

Fast Spiking Low-Threshold Spike Late Spiking Regular Spiking
Interneuron Subtype Mean ± SE n Mean ± SE n Mean ± SE n Mean ± SE n
Vm, mV −76.0 ± 0.9** 70 −67.7 ± 2.3 13 −74.2 ± 1.6 16 −73.2 ± 2.2 10
Input resistance, MΩ 196.4 ± 10.1***,# 71 498.5 ± 54.3### 14 285.0 ± 36.0 16 241.2 ± 19.1*** 10
Action potential
    Amplitude, mV 56.0 ± 1.2 71 63.4 ± 3.8 14 56.0 ± 3.8 16 56.2 ± 4.3 10
    Half-duration, ms 0.6 ± 0.0***,###,† 71 1.1 ± 0.1†† 14 1.1 ± 0.1† 16 0.8 ± 0.0 10
    AHP amplitude, mV 20.5 ± 0.5 71 17.5 ± 1.7 14 17.8 ± 1.2 16 19.4 ± 1.1 10
    AHP half-duration, ms 11.5 ± 0.8***,###,††† 71 55.1 ± 10.3 14 63.7 ± 7.6† 16 42.4 ± 12.6 10
    Rheobase, pA 112.3 ± 7.2*** 71 23.2 ± 4.0# 14 78.1 ± 11.0 16 81.5 ± 21.0 10
Repetitive firing
    Maximal firing rate, Hz 143.0 ± 7.5**,###,† 56 89.5 ± 13.2 14 77.5 ± 12.1 16 95.7 ± 19.0 10
    F–I slope, Hz/pA 0.32 ± 0.03*,# 57 0.15 ± 0.03 14 0.16 ± 0.03 16 0.25 ± 0.05 10

  • Vm, resting membrane potential; AHP, afterhyperpolarization. One-way ANOVA followed by post hoc Tukey's test.

  • ↵* P < 0.05,

  • ↵** P < 0.01,

  • ↵*** P < 0.001 compared with low-threshold spike cell.

  • ↵# P < 0.05,

  • ↵### P < 0.001 compared with late spiking cell.

  • ↵† P < 0.05,

  • ↵†† P < 0.01,

  • ↵††† P < 0.001 compared with regular spiking cell.


Report miscurated data

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Neocortex basket cell Insular cortex Layer 5 Gabaergic fast-spiking VGAT-expressing interneurons input resistance (MΩ) 196.4 ± 10.1 (71) 196.4 (MΩ) Data Table
Neocortex Martinotti cell Insular cortex Layer 5 Gabaergic low thresold spiking VGAT-expressing interneurons input resistance (MΩ) 498.5 ± 54.3 (13) 498.5 (MΩ) Data Table
Neocortex uncharacterized cell Insular cortex Layer 5 Gabaergic late spiking VGAT-expressing interneurons input resistance (MΩ) 285.0 ± 36.0 (16) 285.0 (MΩ) Data Table
Neocortex uncharacterized cell Insular cortex Layer 5 Gabaergic regular spiking VGAT-expressing interneurons input resistance (MΩ) 241.2 ± 19.1 (10) 241.2 (MΩ) Data Table
Neocortex basket cell Insular cortex Layer 5 Gabaergic fast-spiking VGAT-expressing interneurons resting membrane potential (mV) -76.0 ± 0.9 (71) -76.0 (mV) Data Table
Neocortex basket cell Insular cortex Layer 5 Gabaergic fast-spiking VGAT-expressing interneurons spike amplitude (mV) 56.0 ± 1.2 (71) 56.0 (mV) Data Table
Neocortex Martinotti cell Insular cortex Layer 5 Gabaergic low thresold spiking VGAT-expressing interneurons spike amplitude (mV) 63.4 ± 3.8 (13) 63.4 (mV) Data Table
Neocortex uncharacterized cell Insular cortex Layer 5 Gabaergic late spiking VGAT-expressing interneurons spike amplitude (mV) 56.0 ± 3.8 (16) 56.0 (mV) Data Table
Neocortex uncharacterized cell Insular cortex Layer 5 Gabaergic regular spiking VGAT-expressing interneurons spike amplitude (mV) 56.2 ± 4.3 (10) 56.2 (mV) Data Table
Neocortex basket cell Insular cortex Layer 5 Gabaergic fast-spiking VGAT-expressing interneurons spike half-width (ms) 0.6 (71) 0.6 (ms) Data Table
Neocortex Martinotti cell Insular cortex Layer 5 Gabaergic low thresold spiking VGAT-expressing interneurons resting membrane potential (mV) -67.7 ± 2.3 (13) -67.7 (mV) Data Table
Neocortex Martinotti cell Insular cortex Layer 5 Gabaergic low thresold spiking VGAT-expressing interneurons spike half-width (ms) 1.1 ± 0.1 (13) 1.1 (ms) Data Table
Neocortex uncharacterized cell Insular cortex Layer 5 Gabaergic late spiking VGAT-expressing interneurons spike half-width (ms) 1.1 ± 0.1 (16) 1.1 (ms) Data Table
Neocortex uncharacterized cell Insular cortex Layer 5 Gabaergic regular spiking VGAT-expressing interneurons spike half-width (ms) 0.8 (10) 0.8 (ms) Data Table
Neocortex basket cell Insular cortex Layer 5 Gabaergic fast-spiking VGAT-expressing interneurons AHP amplitude (mV) 20.5 ± 0.5 (71) 20.5 (mV) Data Table
Neocortex Martinotti cell Insular cortex Layer 5 Gabaergic low thresold spiking VGAT-expressing interneurons AHP amplitude (mV) 17.5 ± 1.7 (13) 17.5 (mV) Data Table
Neocortex uncharacterized cell Insular cortex Layer 5 Gabaergic late spiking VGAT-expressing interneurons AHP amplitude (mV) 17.8 ± 1.2 (16) 17.8 (mV) Data Table
Neocortex uncharacterized cell Insular cortex Layer 5 Gabaergic regular spiking VGAT-expressing interneurons AHP amplitude (mV) 19.4 ± 1.1 (10) 19.4 (mV) Data Table
Neocortex basket cell Insular cortex Layer 5 Gabaergic fast-spiking VGAT-expressing interneurons AHP duration (ms) 11.5 ± 0.8 (71) 11.5 (ms) Data Table
Neocortex Martinotti cell Insular cortex Layer 5 Gabaergic low thresold spiking VGAT-expressing interneurons AHP duration (ms) 55.1 ± 10.3 (13) 55.1 (ms) Data Table
Neocortex uncharacterized cell Insular cortex Layer 5 Gabaergic late spiking VGAT-expressing interneurons resting membrane potential (mV) -74.2 ± 1.6 (16) -74.2 (mV) Data Table
Neocortex uncharacterized cell Insular cortex Layer 5 Gabaergic late spiking VGAT-expressing interneurons AHP duration (ms) 63.7 ± 7.6 (16) 63.7 (ms) Data Table
Neocortex uncharacterized cell Insular cortex Layer 5 Gabaergic regular spiking VGAT-expressing interneurons AHP duration (ms) 42.4 ± 12.6 (10) 42.4 (ms) Data Table
Neocortex basket cell Insular cortex Layer 5 Gabaergic fast-spiking VGAT-expressing interneurons rheobase (pA) 112.3 ± 7.2 (71) 112.3 (pA) Data Table
Neocortex Martinotti cell Insular cortex Layer 5 Gabaergic low thresold spiking VGAT-expressing interneurons rheobase (pA) 23.2 ± 4.0 (13) 23.2 (pA) Data Table
Neocortex uncharacterized cell Insular cortex Layer 5 Gabaergic late spiking VGAT-expressing interneurons rheobase (pA) 78.1 ± 11.0 (16) 78.1 (pA) Data Table
Neocortex uncharacterized cell Insular cortex Layer 5 Gabaergic regular spiking VGAT-expressing interneurons rheobase (pA) 81.5 ± 21.0 (10) 81.5 (pA) Data Table
Neocortex uncharacterized cell Insular cortex Layer 5 Gabaergic regular spiking VGAT-expressing interneurons resting membrane potential (mV) -73.2 ± 2.2 (10) -73.2 (mV) Data Table
Neocortex basket cell Insular cortex Layer 5 Gabaergic fast-spiking VGAT-expressing interneurons maximum firing rate (Hz) 143.0 ± 7.5 (71) 143.0 (Hz) Data Table
Neocortex Martinotti cell Insular cortex Layer 5 Gabaergic low thresold spiking VGAT-expressing interneurons maximum firing rate (Hz) 89.5 ± 13.2 (13) 89.5 (Hz) Data Table
Neocortex uncharacterized cell Insular cortex Layer 5 Gabaergic late spiking VGAT-expressing interneurons maximum firing rate (Hz) 77.5 ± 12.1 (16) 77.5 (Hz) Data Table
Neocortex uncharacterized cell Insular cortex Layer 5 Gabaergic regular spiking VGAT-expressing interneurons maximum firing rate (Hz) 95.7 ± 19.0 (10) 95.7 (Hz) Data Table
Neocortex basket cell Insular cortex Layer 5 Gabaergic fast-spiking VGAT-expressing interneurons FI slope (Hz/pA) 0.32 ± 0.03 (71) 320.0 (Hz/nA) Data Table
Neocortex Martinotti cell Insular cortex Layer 5 Gabaergic low thresold spiking VGAT-expressing interneurons FI slope (Hz/pA) 0.15 ± 0.03 (13) 150.0 (Hz/nA) Data Table
Neocortex uncharacterized cell Insular cortex Layer 5 Gabaergic late spiking VGAT-expressing interneurons FI slope (Hz/pA) 0.16 ± 0.03 (16) 160.0 (Hz/nA) Data Table
Neocortex uncharacterized cell Insular cortex Layer 5 Gabaergic regular spiking VGAT-expressing interneurons FI slope (Hz/pA) 0.25 ± 0.05 (10) 250.0 (Hz/nA) Data Table