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Article: Spontaneous bursting activity in the developing entorhinal cortex.

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Sheroziya MG; von Bohlen Und Halbach O; Unsicker K; Egorov AV
J. Neurosci., 2009


Table 3.

Quantitative parameters of the plateau potential at different postnatal periods

Parameter (mEC LIII) 1 mm [Ca2+]o
P5–P7(n = 10) Versus P8–P10(n = 6) Versus P11–P13( n = 5)
Plateau duration (s) 4.8 ± 1.8 * 2.8 ± 1.7 ns 2.7 ± 0.7
Plateau amplitude (mV) 9.2 ± 2.3 ns 11.6 ± 3.7 ns 11.3 ± 2.5
Spike frequency withinplateau (Hz) 4.4 ± 1.3 ** 14.8 ± 10.6 ns 11.5 ± 0.6
Number of spikes withinplateau 21 ± 11 ns 32 ± 17 ns 31 ± 6
AHP amplitude (mV) 3.2 ± 0.9 ns 3.4 ± 1.4 ns 4 ± 1.3
AHP duration (s) 12.6 ± 8.5 ns 6.5 ± 2.4 ns 7 ± 4.6
Recording membranepotential (mV) −63.5 ± 3.2 ns −63.1 ± 2.6 ns −62.8 ± 1.3
  • Averaged data are given as mean± SD. The plateau potential was induced by depolarizing current steps (5–10 pA, 0.2–1 s). Recordings were made in ACSF containing 1 mm Ca2+. iGluRs and GABAARs were blocked as detailed in Materials and Methods. Unpaired two-tailed t test or Mann-Whitney rank sum test (versus, i.e., left versus right) values are indicated as follows:

  • *p < 0.05,

  • **p < 0.01. ns, Not significant.


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Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Medial entorhinal cortex layer III pyramidal cell AHP amplitude (mV) 4.0 ± 1.3 4.0 (mV) Data Table
Medial entorhinal cortex layer III pyramidal cell AHP duration (s) 7.0 ± 4.6 7.0 (ms) Data Table
Medial entorhinal cortex layer III pyramidal cell resting membrane potential (mV) -62.8 ± 1.3 -62.8 (mV) Data Table