Cohort/Group | Number of Cells, n | Vrest, mV | Vthresh, mV | Sag, mV | Rinput, MΩ |
---|---|---|---|---|---|
Trained | |||||
Paired | 20 | −65.2 ± 0.8 | −42.9 ± 2.6 | −3.7 ± 0.2 | 72.1 ± 4.5 |
Shock | 19 | −65.2 ± 1.0 | −39.4 ± 2.7 | −3.3 ± 0.3 | 88.6 ± 3.9* |
Tone | 26 | −66.8 ± 0.7 | −43.7 ± 2.4 | −4.1 ± 0.3 | 78.0 ± 4.9 |
Naïve | 19 | −67.0 ± 0.6 | −45.6 ± 1.5 | −3.8 ± 0.2 | 70.9 ± 4.8 |
Extinguished | 20 | −64.3 ± 0.8 | −35.1 ± 4.4** | −3.8 ± 0.3 | 80.7 ± 5.6 |
Tested | |||||
Paired | 22 | −64.3 ± 0.7 | −45.8 ± 1.4 | −3.5 ± 0.3 | 71.0 ± 5.0 |
Shock | 22 | −65.0 ± 0.5 | −42.6 ± 2.0 | −3.5 ± 0.3 | 67.8 ± 5.0 |
Tone | 19 | −65.2 ± 0.9 | −41.3 ± 1.5 | −4.3 ± 0.3 | 78.3 ± 3.3 |
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Values are means ± SE. Resting potential (Vrest), action potential threshold (Vthresh), and input resistance (Rinput) were measured for every cell. Vrest was calculated as the potential with 0-pA current current injection; Vthresh was calculated as the voltage where the first derivative of the action potential equaled 20 mV/ms; Rinput was calculated as the slope of the I–V curve generated with an 800-ms current injection from −0.3 to +0.1 nA; Sag was measured as the difference between the peak and steady-state hyperpolarization in response to an 800-ms, −300-PA current step.
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↵* = F(7,159) = 1.98, P = 0.062;
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↵* = F(7,159) = 1.85, P = 0.081.