AboutNeuron TypesElectrophysiology PropertiesArticlesFAQsData/APIGet Involved

Article: Diversity of layer 5 projection neurons in the mouse motor cortex.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Oswald MJ; Tantirigama ML; Sonntag I; Hughes SM; Empson RM
Front Cell Neurosci, 2013


Morphological characteristics of M1 layer 5 projection neurons.

CSp (n = 19) CTh (n = 20) CStr (n = 16) CC (n = 23) Statistics
Cell depth 0.67 ±0.01 0.51 ±0.02 0.52 ±0.02 0.48 ±0.01 a3, b3, c3
Soma size (μm) 19.7 ±0.6 18.5 ±0.6 15.4 ±0.4 16.1 ±0.7 b3, c3, d2, e1
Soma height/width ratio 1.47 ±0.04 1.46 ±0.05 1.42 ±0.06 1.29 ±0.04 c1, e1
Apical dendrite height§ 0.97 (0.96, 0.98) 0.98 (0.97, 0.98) 0.94 (0.91, 0.96) 0.93 (0.85, 0.98) b1, d3, e2
Tuft origin§ 0.45 (0.35, 0.61) 0.55 (0.43, 0.63) 0.70 (0.63, 0.75) 0.68 (0.64, 0.75) b3, c3, d1, e2
Tuft height (μm) 509 (315, 594) 283 (189, 362) 153 (128, 185) 140 (92, 185) b3, c3, d1, e3
Tuft width (μm) 379 ±21 429 ±29 191 ±27 160 ±20 b3, c3, d3, e3

CSp, corticospinal neurons; CTh, corticothalamic neurons; CStr, callosal corticostriatal neurons; CC, callosal corticocortical neurons.

One-way ANOVA and Tukey’s post hoc test for multiple comparisons on normally distributed data (mean ±SEM), otherwise non-parametric Kruskal-Wallis test and Dunn’s post hoc analysis (median values with the 1st and 3rd quartile stated in brackets); a, CSp vs CTh; b, CSp vs CStr; c, CSp vs CC; d, CTh vs CStr; e, CTh vs CC; f, CStr vs CC; 1p < 0.05, 2p < 0.01, 3p < 0.001.

Normalized to cortical width.

Normalized to cell depth from the pia.


Report miscurated data

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source