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Article: Dopamine modulates the responsivity of mediodorsal thalamic cells recorded in vitro.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Lavin A; Grace AA J. Neurosci., 1998
Table 1.
Effect of D1 agonist SKF 38393 and D1 antagonist SCH 23390 on basic membrane properties of thalamic cells
| Effects of SKF 38393 (n = 11) | Effects of SCH 23390 (n = 4) | ||||
|---|---|---|---|---|---|
| Control | SKF 38393 | Control | SKF 38393 | SCH 23390 | |
| Membrane potential (mV) | 68.3 ± 8.7 | 68.7 ± 9.8 | 67.6 ± 12.6 | 66.9 ± 13.7 | 62.7 ± 15.4 |
| Input resistance (MΩ) | 45.5 ± 19.0 | 39.3 ± 14.4 | 58.2 ± 21.4 | 42.2 ± 12.5 | 56.2 ± 15.0 |
| Spike threshold (mV) | 52.0 ± 8.1 | 46.7 ± 5.7 | 46.9 ± 8.4 | 44.7 ± 5.3 | 38.6 ± 7.0 |
| Current threshold (nA) | 0.44 ± 0.23 | 0.32 ± 0.14 | 0.55 ± 0.15 | 0.28 ± 0.17 | 0.42 ± 0.22 |
| LTS-evoked (rebound) | 3/9 | 4/11 | 2/4 | 2/4 | |
Inferred neuron-electrophysiology data values
| Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
|---|---|---|---|---|---|
| Thalamus relay cell | mediodorsal nucleus thalamus relay cell | spike threshold (mV) | 52.0 ± 8.1 (11) | -52.0 (mV) | Data Table |
| Thalamus relay cell | mediodorsal nucleus thalamus relay cell | resting membrane potential (mV) | 68.3 ± 8.7 (11) | -68.3 (mV) | Data Table |
| Thalamus relay cell | mediodorsal nucleus thalamus relay cell | rheobase (nA) | 0.44 ± 0.23 (11) | 440.0 (pA) | Data Table |
| Thalamus relay cell | mediodorsal nucleus thalamus relay cell | input resistance (MΩ) | 45.5 ± 19.0 (11) | 45.5 (MΩ) | Data Table |