AboutNeuron TypesElectrophysiology PropertiesArticlesFAQsData/APIGet Involved

Article: Subdivision-specific responses of neurons in the nucleus of the tractus solitarius to activation of mu-opioid receptors in the rat.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Poole SL; Deuchars J; Lewis DI; Deuchars SA
J. Neurophysiol., 2007



TABLE 1.Electrophysiological characteristics of NTS neurons responsive and unresponsive to DAMGO
Subdivision Response to DAMGO Action Potential
 AHP
Duration, ms Halfwidth, ms Amplitude, mV 1 phase 2 phase Duration, ms Amplitude, mV
DM Yes 5.4 ± 1.2 2.7 ± 0.6 69.0 ± 8.5 3/5 2/5 63.8 ± 7.8 22.9 ± 3.8
DM No 6.4 ± 0.8 3.1 ± 0.4 73.6 ± 3.3 4/5 1/5 37.5 ± 8.3*** 16.9 ± 1.4
DL Yes 6.0 ± 0.7 2.9 ± 0.3 61.2 ± 3.7 5/7 2/7 65.4 ± 8.4 25.1 ± 3.1
DL No 5.0 ± 0.7 2.6 ± 0.4 72.7 ± 2.7 1/7 6/7 38.2 ± 5.9*** 16.8 ± 2.1***
M Yes 4.6 ± 0.5 2.4 ± 0.3 76.1 ± 3.3 8/10 2/10 49.2 ± 9.3 21.9 ± 1.9
M No 5.3 ± 0.4 2.5 ± 0.2 78.7 ± 2.1 9/10 1/10 52.3 ± 8.5 18.8 ± 1.8
Mean values = SE showing action potential duration, amplitude, and half- width and afterhyperpolarization (AHP) amplitude and duration. The shape of the AHP after an action potential, i.e. whether they were single component (1 phase) or had two components differentiated by the slope of the decay phase (2-phase) were also determined for both [D-Ala2, N-Me-Phe4, Gly5-ol]-enkephalin (DAMGO) responsive and unresponsive neurons in the dorsomedial (DM), dorsolateral (DL), and medial (M) nucleus tractus soltarius (NTS). In the dorsomedial subdivision, there is a significant difference (P < 0.05) in AHP duration in unresponsive neurons compared to responsive neurons. In the dorsolateral subdivision, there were significant differences in the AHP amplitude (P < 0.05) and duration (P < 0.05) in responsive and unresponsive neurons.

Report miscurated data

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Nucleus of the solitary tract principal cell Dorsomedial nucleus of the tractus solitarius neurons that respond to DAMGO injection spike width (ms) 5.4 ± 1.2 (6) 5.4 (ms) Data Table
Nucleus of the solitary tract principal cell Dorsomedial nucleus of the tractus solitarius neurons that respond to DAMGO injection spike half-width (ms) 2.7 ± 0.6 (6) 2.7 (ms) Data Table
Nucleus of the solitary tract principal cell Dorsomedial nucleus of the tractus solitarius neurons that respond to DAMGO injection spike amplitude (mV) 69.0 ± 8.5 (6) 69.0 (mV) Data Table
Nucleus of the solitary tract principal cell Dorsomedial nucleus of the tractus solitarius neurons that respond to DAMGO injection AHP duration (ms) 63.8 ± 7.8 (6) 63.8 (ms) Data Table
Nucleus of the solitary tract principal cell Dorsomedial nucleus of the tractus solitarius neurons that respond to DAMGO injection AHP amplitude (mV) 22.9 ± 3.8 (6) 22.9 (mV) Data Table
Nucleus of the solitary tract principal cell Dorsomedial nucleus of the tractus solitarius neurons that do not respond to DAMGO injection spike width (ms) 6.4 ± 0.8 (23) -- Data Table
Nucleus of the solitary tract principal cell Dorsomedial nucleus of the tractus solitarius neurons that do not respond to DAMGO injection spike half-width (ms) 3.1 ± 0.4 (23) -- Data Table
Nucleus of the solitary tract principal cell Dorsomedial nucleus of the tractus solitarius neurons that do not respond to DAMGO injection spike amplitude (mV) 73.6 ± 3.3 (23) -- Data Table
Nucleus of the solitary tract principal cell Dorsomedial nucleus of the tractus solitarius neurons that do not respond to DAMGO injection AHP duration (ms) 37.5 ± 8.3 (23) -- Data Table
Nucleus of the solitary tract principal cell Dorsomedial nucleus of the tractus solitarius neurons that do not respond to DAMGO injection AHP amplitude (mV) 16.9 ± 1.4 (23) -- Data Table
Nucleus of the solitary tract intrinsic cell Dorsolateral nucleus of the tractus solitarius neurons that respond to DAMGO injection spike width (ms) 6.0 ± 0.7 (10) -- Data Table
Nucleus of the solitary tract intrinsic cell Dorsolateral nucleus of the tractus solitarius neurons that respond to DAMGO injection spike half-width (ms) 2.9 ± 0.3 (10) -- Data Table
Nucleus of the solitary tract intrinsic cell Dorsolateral nucleus of the tractus solitarius neurons that respond to DAMGO injection spike amplitude (mV) 61.2 ± 3.7 (10) -- Data Table
Nucleus of the solitary tract intrinsic cell Dorsolateral nucleus of the tractus solitarius neurons that respond to DAMGO injection AHP duration (ms) 65.4 ± 8.4 (10) -- Data Table
Nucleus of the solitary tract intrinsic cell Dorsolateral nucleus of the tractus solitarius neurons that respond to DAMGO injection AHP amplitude (mV) 25.1 ± 3.1 (10) -- Data Table
Nucleus of the solitary tract principal cell Dorsolateral nucleus of the tractus solitarius neurons that do not respond to DAMGO injection spike width (ms) 5.0 ± 0.7 (9) -- Data Table
Nucleus of the solitary tract principal cell Dorsolateral nucleus of the tractus solitarius neurons that do not respond to DAMGO injection spike half-width (ms) 2.6 ± 0.4 (9) -- Data Table
Nucleus of the solitary tract principal cell Dorsolateral nucleus of the tractus solitarius neurons that do not respond to DAMGO injection spike amplitude (mV) 72.7 ± 2.7 (9) -- Data Table
Nucleus of the solitary tract principal cell Dorsolateral nucleus of the tractus solitarius neurons that do not respond to DAMGO injection AHP duration (ms) 38.2 ± 5.9 (9) -- Data Table
Nucleus of the solitary tract principal cell Dorsolateral nucleus of the tractus solitarius neurons that do not respond to DAMGO injection AHP amplitude (mV) 16.8 ± 2.1 (9) -- Data Table
Nucleus of the solitary tract principal cell Medial nucleus of the tractus solitarius neurons that respond to DAMGO injection spike width (ms) 4.6 ± 0.5 (34) -- Data Table
Nucleus of the solitary tract principal cell Medial nucleus of the tractus solitarius neurons that respond to DAMGO injection spike half-width (ms) 2.4 ± 0.3 (34) -- Data Table
Nucleus of the solitary tract principal cell Medial nucleus of the tractus solitarius neurons that respond to DAMGO injection spike amplitude (mV) 76.1 ± 3.3 (34) -- Data Table
Nucleus of the solitary tract principal cell Medial nucleus of the tractus solitarius neurons that respond to DAMGO injection AHP duration (ms) 49.2 ± 9.3 (34) -- Data Table
Nucleus of the solitary tract principal cell Medial nucleus of the tractus solitarius neurons that respond to DAMGO injection AHP amplitude (mV) 21.9 ± 1.9 (34) -- Data Table
Nucleus of the solitary tract principal cell Medial nucleus of the tractus solitarius neurons that do not respond to DAMGO injection spike width (ms) 5.3 ± 0.4 (46) -- Data Table
Nucleus of the solitary tract principal cell Medial nucleus of the tractus solitarius neurons that do not respond to DAMGO injection spike half-width (ms) 2.5 ± 0.2 (46) -- Data Table
Nucleus of the solitary tract principal cell Medial nucleus of the tractus solitarius neurons that do not respond to DAMGO injection spike amplitude (mV) 78.7 ± 2.1 (46) -- Data Table
Nucleus of the solitary tract principal cell Medial nucleus of the tractus solitarius neurons that do not respond to DAMGO injection AHP duration (ms) 52.3 ± 8.5 (46) -- Data Table
Nucleus of the solitary tract principal cell Medial nucleus of the tractus solitarius neurons that do not respond to DAMGO injection AHP amplitude (mV) 18.8 ± 1.8 (46) -- Data Table