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Article: Optogenetic inhibition of chemically induced hypersynchronized bursting in mice.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Berglind F; Ledri M; Sørensen AT; Nikitidou L; Melis M; Bielefeld P; Kirik D; Deisseroth K; Andersson M; Kokaia M
Neurobiol. Dis., 2014


Control (n = 6)NpHR3 (n = 6)
RMP (mV)- 79.9 (4.6)- 78.8 (3.5)
Input resistance (MΩ)214.5 (78.5)289.9(70.4)
AP threshold (mV)- 37.2 (2.3)- 36.3 (2.1)
Rheobase (pA)297.2 (87.4)289.9 (30.6)
AP amplitude (mV)85.6 (4.5)88.2 (5.2)
AP half duration (ms)1.1 (0.2)1.0 (0.1)
Photocurrent (pA)-306.1 (221.9)
Light-induced hyperpolarization (mV)-24.4 (22.2)

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Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Hippocampus CA3 pyramidal cell rheobase (pA) 297.2 297.2 (pA) Data Table
Hippocampus CA3 pyramidal cell spike amplitude (mV) 85.6 85.6 (mV) Data Table
Hippocampus CA3 pyramidal cell spike half-width (ms) 1.1 1.1 (ms) Data Table
Hippocampus CA3 pyramidal cell resting membrane potential (mV) -79.9 -79.9 (mV) Data Table
Hippocampus CA3 pyramidal cell input resistance (MΩ) 214.5 214.5 (MΩ) Data Table
Hippocampus CA3 pyramidal cell spike threshold (mV) -37.2 -37.2 (mV) Data Table