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Article: Sleep impairment and reduced interneuron excitability in a mouse model of Dravet Syndrome.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Kalume F; Oakley JC; Westenbroek RE; Gile J; de la Iglesia HO; Scheuer T; Catterall WA
Neurobiol. Dis., 2015


GenotypeAP threshold (mV)AP width (ms)AP peak voltage (mV)Input resistance (MΩ)
WT- 35.1 ± 1.08.5 ± 0.440.6 ± 6.075.0 ± 9.0
HET- 37.7 ± 1.08.6 ± 0.735.1 ± 6.069.8 ± 11
KO- 38.1 ± 1.08.6 ± 0.433.2 ± 5.071.8 ± 9.0

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Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Thalamic reticular nucleus cell Reticular Nucleus of the Thalamus GABAergic Neuron spike threshold (mV) -35.1 ± 1.0 -35.1 (mV) Data Table
Thalamic reticular nucleus cell Reticular Nucleus of the Thalamus GABAergic Neuron spike width (ms) 8.5 ± 0.4 8.5 (ms) Data Table
Thalamic reticular nucleus cell Reticular Nucleus of the Thalamus GABAergic Neuron spike peak (mV) 40.6 ± 6.0 40.6 (mV) Data Table
Thalamic reticular nucleus cell Reticular Nucleus of the Thalamus GABAergic Neuron input resistance (MΩ) 75.0 ± 9.0 75.0 (MΩ) Data Table