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Article: Active and passive membrane properties of rat sympathetic preganglionic neurones innervating the adrenal medulla.

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Wilson JM; Coderre E; Renaud LP; Spanswick D
J. Physiol. (Lond.), 2002


Table 1

Summary of membrane properties of SPN innervating the adrenal medulla

Membrane property n
Resting membrane potential (mV) −62.2 ± 5.7 54
Input resistance (MΩ) 410 ± 241 54
Action potential amplitude (mV) 88.5 ± 15.6 54
Action potential duration (ms) 5.7 ± 1.8 54
After-hyperpolarisation amplitude (mV) 25.9 ± 6.8 54
After-hyperpolarisation 90-10% decay time (ms) 297.7 ± 150.2 54
Presence of shoulder on action potential repolarisation phase 100% 54/54
Presence of transient outward rectification 96% 52/54
Presence of anomalous inward rectification 89% 48/54
  • Whole-cell recordings were made from 54 SPN identified as innervating the adrenal medulla by the presence of a retrograde label, rhodamine dextran lysine (RDL) injected into the adrenal medulla and a second label Lucifer Yellow or Alexa 594 introduced from the recording electrode. The table summarises data obtained from these neurons. Results are expressed as means ± s.d. except for the descriptive data that are described as percentage of neurons that expressed a particular active conductance indicated in the table.


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Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Spinal cord intermediate horn motor neuron sympathetic AHP duration (ms) 5.7 ± 1.8 5.7 (ms) Data Table
Spinal cord intermediate horn motor neuron sympathetic AHP amplitude (mV) 25.9 ± 6.8 25.9 (mV) Data Table
Spinal cord intermediate horn motor neuron sympathetic resting membrane potential (mV) -62.2 ± 5.7 -62.2 (mV) Data Table
Spinal cord intermediate horn motor neuron sympathetic input resistance (MΩ) 410.0 ± 241.0 410.0 (MΩ) Data Table
Spinal cord intermediate horn motor neuron sympathetic spike amplitude (mV) 88.5 ± 15.6 88.5 (mV) Data Table