AboutNeuron TypesElectrophysiology PropertiesArticlesFAQsData/APIGet Involved

Article: Resilient RTN fast spiking in Kv3.1 null mice suggests redundancy in the action potential repolarization mechanism.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Porcello DM; Ho CS; Joho RH; Huguenard JR
J. Neurophysiol., 2002


Table 1.

Cell properties and single-action potential characteristics for wt and Kv3.1−/− RTN neurons

Wild-Type Kv3.1−/−
Membrane potential, mV −75.9 ± 1.7 −73.5 ± 2.3
Input resistance, MΩ 273.8 ± 26.8 273.5 ± 26.2
23°C
 AP amplitude, mV 80.8 ± 1.8 75.7 ± 1.5*
 AP max rate of depolarization, V/s 350.6 ± 14.6 330.1 ± 10.6
 AP max rate of repolarization, V/s −241.4 ± 13.3 −229.1 ± 7.8
 AP half-width, ms 0.46 ± 0.02 0.43 ± 0.01
 AP fAHP, mV −20.2 ± 1.2 −16.9 ± 0.9*
 AP threshold, mV −50.9 ± 3.6 −50.1 ± 3.7
34°C
 AP amplitude, mV 67.4 ± 1.5 61.1 ± 3.0
 AP max rate of depolarization, V/s 515.4 ± 25.8 449.5 ± 26.1
 AP max rate of repolarization, V/s −543.5 ± 49.6 −381.7 ± 18.21-160
 AP half-width, ms 0.19 ± 0.01 0.23 ± 0.011-165
 AP fAHP, mV −22.3 ± 1.3 −20.3 ± 1.4
 AP threshold, mV −47.5 ± 1.1 −47.1 ± 1.7

  • Values are means ± SE. wt, wild-type; RTN, reticular thalamic nucleus; AP, action potential; fAHP, fast afterhyperpolarization.

  • ↵*  P < 0.05,

  • ↵F1-160  P < 0.01,

  • ↵F1-165  P < 0.005.


Report miscurated data

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Thalamic reticular nucleus cell Thalamic reticular nucleus fast-spiking GABAergic cell spike amplitude (mV) 80.8 ± 1.8 (16) 80.8 (mV) Data Table
Thalamic reticular nucleus cell Thalamic reticular nucleus fast-spiking GABAergic cell spike max rise slope (V/s) 350.6 ± 14.6 (16) 350.6 (mV/ms) Data Table
Thalamic reticular nucleus cell Thalamic reticular nucleus fast-spiking GABAergic cell spike max decay slope (V/s) -241.4 ± 13.3 (16) 241.4 (mV/ms) Data Table
Thalamic reticular nucleus cell Thalamic reticular nucleus fast-spiking GABAergic cell resting membrane potential (mV) -75.9 ± 1.7 (16) -75.9 (mV) Data Table
Thalamic reticular nucleus cell Thalamic reticular nucleus fast-spiking GABAergic cell spike half-width (ms) 0.46 ± 0.02 (16) 0.46 (ms) Data Table
Thalamic reticular nucleus cell Thalamic reticular nucleus fast-spiking GABAergic cell fast AHP amplitude (mV) -20.2 ± 1.2 (16) 20.2 (mV) Data Table
Thalamic reticular nucleus cell Thalamic reticular nucleus fast-spiking GABAergic cell spike threshold (mV) -50.9 ± 3.6 (16) -50.9 (mV) Data Table
Thalamic reticular nucleus cell Thalamic reticular nucleus fast-spiking GABAergic cell spike amplitude (mV) 67.4 ± 1.5 (16) 67.4 (mV) Data Table
Thalamic reticular nucleus cell Thalamic reticular nucleus fast-spiking GABAergic cell spike max rise slope (V/s) 515.4 ± 25.8 (16) 515.4 (mV/ms) Data Table
Thalamic reticular nucleus cell Thalamic reticular nucleus fast-spiking GABAergic cell spike max decay slope (V/s) -543.5 ± 49.6 (16) 543.5 (mV/ms) Data Table
Thalamic reticular nucleus cell Thalamic reticular nucleus fast-spiking GABAergic cell spike half-width (ms) 0.19 ± 0.01 (16) 0.19 (ms) Data Table
Thalamic reticular nucleus cell Thalamic reticular nucleus fast-spiking GABAergic cell fast AHP amplitude (mV) -22.3 ± 1.3 (16) 22.3 (mV) Data Table
Thalamic reticular nucleus cell Thalamic reticular nucleus fast-spiking GABAergic cell spike threshold (mV) -47.5 ± 1.1 (16) -47.5 (mV) Data Table
Thalamic reticular nucleus cell Thalamic reticular nucleus fast-spiking GABAergic cell input resistance (MΩ) 273.8 ± 26.8 (16) 273.8 (MΩ) Data Table