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Article: Reduced Hyperpolarization-Activated Current Contributes to Enhanced Intrinsic Excitability in Cultured Hippocampal Neurons from PrP(-/-) Mice.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Fan J; Stemkowski PL; Gandini MA; Black SA; Zhang Z; Souza IA; Chen L; Zamponi GW Front Cell Neurosci, 2016
Metadata values
| Experimental condition | Value |
|---|---|
| ElectrodeType | Patch-clamp |
| RecTemp | 20.0 - 24.0 |
| AnimalAge | 0.0 - 1.0 |
| InternalSolution | 5.0 |
| ExternalSolution | 5.0 |
| Species | Mice |
| Strain | C57BL |
| PrepType | cell culture |
| JxnPotential | Unreported |
| internal_0_pH | 7.2 |
| internal_0_Mg | 4.0 |
| internal_0_Na | 0.3 |
| internal_0_K | 130.0 |
| internal_0_GTP | 0.3 |
| internal_0_ATP | 4.0 |
| internal_0_EGTA | 10.0 |
| internal_0_HEPES | 10.0 |
| internal_0_Cl | 4.0 |
| internal_0_Ca | 2.0 |
| external_0_pH | 7.4 |
| external_0_Mg | 1.0 |
| external_0_Na | 150.0 |
| external_0_K | 5.0 |
| external_0_HEPES | 10.0 |
| external_0_Cl | 162.0 |
| external_0_Ca | 2.5 |
| external_0_glucose | 10.0 |