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Article: Alpha-synuclein overexpression in mice alters synaptic communication in the corticostriatal pathway.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Wu N; Joshi PR; Cepeda C; Masliah E; Levine MS
J. Neurosci. Res., 2010

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Neostriatum medium spiny neuron cell capacitance (pF) 95.0 ± 3.0 (27) 95.0 (pF) Data Table
Neostriatum medium spiny neuron cell capacitance (pF) 96.0 ± 4.0 (8) 96.0 (pF) Data Table
Neostriatum medium spiny neuron cell capacitance (pF) 95.0 ± 3.0 (14) 95.0 (pF) Data Table
Neostriatum medium spiny neuron input resistance (MΩ) 105.0 ± 8.0 (27) 105.0 (MΩ) Data Table
Neostriatum medium spiny neuron input resistance (MΩ) 105.0 ± 8.0 (8) 105.0 (MΩ) Data Table
Neostriatum medium spiny neuron input resistance (MΩ) 137.0 ± 11.0 (14) 137.0 (MΩ) Data Table
Neostriatum medium spiny neuron membrane time constant (ms) 1.6 ± 0.1 (8) 1.6 (ms) Data Table
Neostriatum medium spiny neuron membrane time constant (ms) 1.6 ± 0.1 (14) 1.6 (ms) Data Table
Neostriatum medium spiny neuron membrane time constant (ms) 1.6 ± 0.1 (27) 1.6 (ms) Data Table

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Metadata values

Experimental condition Value
Species Mice
ElectrodeType Patch-clamp
PrepType in vitro
AnimalAge 30.0 - 300.0
ExternalSolution 5.0
InternalSolution 5.0
internal_1_pH 7.4
internal_1_Mg 2.0
internal_1_Ca 0.1
internal_1_Cl 6.2
internal_1_K 2.0
internal_2_pH 7.4
internal_2_Mg 2.0
internal_2_Ca 1.0
internal_2_Na 140.0
internal_2_Cl 148.0
internal_2_K 2.0
internal_3_pH 7.25
internal_3_Mg 2.0
internal_3_Na 4.4
internal_3_Cl 4.0
external_1_pH 7.4
external_1_Ca 2.0
external_1_Na 135.0
external_1_Cl 165.0
Strain Other
JxnPotential Unreported
RecTemp 25.0 ± 2.0
internal_0_pH 7.275
internal_0_Mg 6.0
internal_0_Na 24.0
internal_0_GTP 0.5
internal_0_ATP 5.0
internal_0_EGTA 5.0
internal_0_HEPES 10.0
internal_0_Cl 16.0
internal_0_Cs 140.0
external_0_pH 7.3
external_0_Mg 2.0
external_0_Cl 8.0
external_0_Ca 2.0

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
20248 Alpha-synuclein overexpression in mice alters synaptic communication in the corticostriatal pathway. Wu N; Joshi PR; Cepeda C; Masliah E; Levine MS J. Neurosci. Res. 2010 False 3 Brenna Li, Ellie Hogan, 1