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Article: Activity-dependent depression of the spike after-depolarization generates long-lasting intrinsic plasticity in hippocampal CA3 pyramidal neurons.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Brown JT; Randall AD
J. Physiol. (Lond.), 2009

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Hippocampus CA3 pyramidal cell ADP amplitude 15.2 ± 0.5 (95) 15.2 (mV) Data Table
Hippocampus CA3 pyramidal cell input resistance (*) 167.0 ± 4.0 (95) -- Data Table
Hippocampus CA3 pyramidal cell input resistance (*) 204.0 ± 5.0 (95) -- Data Table
Hippocampus CA3 pyramidal cell membrane time constant (*) 48.4 ± 1.3 (95) -- Data Table
Hippocampus CA3 pyramidal cell resting membrane potential -75.0 ± 1.0 (95) -75.0 (mV) Data Table
Hippocampus CA3 pyramidal cell sag ratio (*) 17.3 ± 1.1 (95) -- Data Table
Hippocampus CA3 pyramidal cell spike half-width (at) 0.57 ± 0.01 (95) -- Data Table
Hippocampus CA3 pyramidal cell spike peak 29.0 ± 0.5 (95) 29.0 (mV) Data Table
Hippocampus CA3 pyramidal cell spike threshold -58.1 ± 0.3 (95) -58.1 (mV) Data Table

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Metadata values

Experimental condition Value
Species Rats
ElectrodeType Patch-clamp
PrepType in vitro
Strain Wistar
RecTemp 32.0 ± 1.0
ExternalSolution 5.0
InternalSolution 5.0
JxnPotential Corrected
AnimalAge 14.0 - 21.0
JxnOffset 13.0
internal_0_pH 7.3
internal_0_Mg 4.0
internal_0_Na 0.3
internal_0_K 160.0
internal_0_GTP 0.3
internal_0_ATP 4.0
internal_0_EGTA 0.2
internal_0_HEPES 10.0
internal_0_Cl 20.0
external_0_Mg 1.0
external_0_Na 151.25
external_0_K 3.0
external_0_Cl 131.0
external_0_Ca 2.0
external_0_glucose 10.0
external_0_gabazine 10.0
external_0_picro 50.0
external_0_NBQX 1.0

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
8308 Activity-dependent depression of the spike after-depolarization generates long-lasting intrinsic plasticity in hippocampal CA3 pyramidal neurons. Brown JT; Randall AD J. Physiol. (Lond.) 2009 False 8 Shreejoy Tripathy, Brenna Li, Hannah Sangra, 2