AboutNeuron TypesElectrophysiology PropertiesArticlesFAQsData/APIGet Involved

Article: Differential electrophysiological properties of dopamine D1 and D2 receptor-containing striatal medium-sized spiny neurons.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Cepeda C; André VM; Yamazaki I; Wu N; Kleiman-Weiner M; Levine MS
Eur. J. Neurosci., 2008

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Neostriatum medium spiny neuron Neostriatum Drd2-expressing, indirect projecting, medium spiny neuron AHP amplitude (mV) 6.6 ± 0.87 (65) 6.6 (mV) Data Table
Neostriatum medium spiny neuron Neostriatum Drd1-expressing, direct projecting, medium spiny neuron AHP amplitude (mV) 8.2 ± 0.46 (40) 8.2 (mV) Data Table
Neostriatum medium spiny neuron Neostriatum Drd2-expressing, indirect projecting, medium spiny neuron cell capacitance (pF) 72.4 ± 2.2 (65) 72.4 (pF) Data Table
Neostriatum medium spiny neuron Neostriatum Drd1-expressing, direct projecting, medium spiny neuron cell capacitance (pF) 70.1 ± 3.3 (40) 70.1 (pF) Data Table
Neostriatum medium spiny neuron Neostriatum Drd1-expressing, direct projecting, medium spiny neuron input resistance (MΩ) 186.7 ± 19.9 (40) 186.7 (MΩ) Data Table
Neostriatum medium spiny neuron Neostriatum Drd2-expressing, indirect projecting, medium spiny neuron input resistance (MΩ) 181.2 ± 15.3 (65) 181.2 (MΩ) Data Table
Neostriatum medium spiny neuron Neostriatum Drd1-expressing, direct projecting, medium spiny neuron membrane time constant (ms) 1.6 ± 0.1 (40) 1.6 (ms) Data Table
Neostriatum medium spiny neuron Neostriatum Drd2-expressing, indirect projecting, medium spiny neuron membrane time constant (ms) 1.5 ± 0.1 (65) 1.5 (ms) Data Table
Neostriatum medium spiny neuron Neostriatum Drd2-expressing, indirect projecting, medium spiny neuron resting membrane potential (mV) -82.2 ± 1.2 (65) -82.2 (mV) Data Table
Neostriatum medium spiny neuron Neostriatum Drd1-expressing, direct projecting, medium spiny neuron resting membrane potential (mV) -82.1 ± 1.4 (40) -82.1 (mV) Data Table
Neostriatum medium spiny neuron Neostriatum Drd1-expressing, direct projecting, medium spiny neuron spike amplitude (mV) 86.0 (40) 86.0 (mV) Data Table
Neostriatum medium spiny neuron Neostriatum Drd2-expressing, indirect projecting, medium spiny neuron spike amplitude (mV) 87.0 (65) 87.0 (mV) Data Table
Neostriatum medium spiny neuron Neostriatum Drd2-expressing, indirect projecting, medium spiny neuron spike half-width (ms) 1.16 ± 0.04 (65) 1.16 (ms) Data Table
Neostriatum medium spiny neuron Neostriatum Drd1-expressing, direct projecting, medium spiny neuron spike half-width (ms) 1.13 ± 0.05 (40) 1.13 (ms) Data Table
Neostriatum medium spiny neuron Neostriatum Drd1-expressing, direct projecting, medium spiny neuron spike threshold (mV) -48.4 ± 1.5 (40) -48.4 (mV) Data Table
Neostriatum medium spiny neuron Neostriatum Drd2-expressing, indirect projecting, medium spiny neuron spike threshold (mV) -53.0 ± 1.3 (65) -53.0 (mV) Data Table

Report miscurated data

Metadata values

Experimental condition Value
Species Mice
ElectrodeType Patch-clamp
PrepType in vitro
Strain Mouse, Transgenic
InternalSolution 5.0
ExternalSolution 5.0
internal_1_pH 7.4
internal_1_Mg 2.0
internal_1_Ca 1.0
internal_1_Na 140.0
internal_1_Cl 160.8
internal_1_K 2.0
internal_2_pH 7.25
internal_2_Mg 2.0
internal_2_Na 4.4
internal_2_Cl 4.0
external_1_pH 7.4
external_1_Ca 2.0
external_1_Na 135.0
external_1_Cl 165.0
JxnPotential Unreported
AnimalAge 28.0 - 48.0
RecTemp 20.0 - 24.0
internal_0_Mg 2.0
internal_0_K 144.0
internal_0_ATP 2.0
internal_0_HEPES 2.0
internal_0_Cl 4.2
internal_0_Ca 0.1
external_0_pH 7.4
external_0_Mg 2.0
external_0_Na 157.25
external_0_K 3.0
external_0_Cl 141.0
external_0_Ca 2.0
external_0_glucose 10.0

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
48872 Differential electrophysiological properties of dopamine D1 and D2 receptor-containing striatal medium-sized spiny neurons. Cepeda C; André VM; Yamazaki I; Wu N; Kleiman-Weiner M; Levine MS Eur. J. Neurosci. 2008 False 8 Shreejoy Tripathy, Brenna Li, Athanasios Kritharis, 2