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Article: Differences in intrinsic properties and local network connectivity of identified layer 5 and layer 6 adult mouse auditory corticothalamic neurons support a dual corticothalamic projection hypothesis.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Llano DA; Sherman SM
Cereb. Cortex, 2009

Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Neocortex pyramidal cell layer 5-6 Auditory cortex layer 5 corticothalamic pyramidal neurons adaptation ratio (1 – first/last ISI) 0.18 ± 0.14 (13) 0.18 (ratio) Data Table
Neocortex pyramidal cell layer 5-6 Auditory cortex layer 6 corticothalamic regular firing pyramidal neurons adaptation ratio (1 – first/last ISI) 0.35 ± 0.13 (21) 0.35 (ratio) Data Table
Neocortex pyramidal cell layer 5-6 Auditory cortex layer 5 corticothalamic pyramidal neurons ADP amplitude (mV) 2.1 ± 2.5 (47) 2.1 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Auditory cortex layer 6 corticothalamic regular firing pyramidal neurons ADP amplitude (mV) 0.4 ± 1.0 (24) 0.4 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Auditory cortex layer 6 corticothalamic regular firing pyramidal neurons cell surface area 100.0 ± 34.0 (9) 100.0 (m) Data Table
Neocortex pyramidal cell layer 5-6 Auditory cortex layer 5 corticothalamic pyramidal neurons cell surface area 193.0 ± 53.0 (12) 193.0 (m) Data Table
Neocortex pyramidal cell layer 5-6 Auditory cortex layer 6 corticothalamic regular firing pyramidal neurons fast AHP amplitude (mV) 8.8 ± 4.7 (24) 8.8 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Auditory cortex layer 5 corticothalamic pyramidal neurons fast AHP amplitude (mV) 4.0 ± 3.7 (47) 4.0 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Auditory cortex layer 6 corticothalamic regular firing pyramidal neurons input resistance (MΩ) 216.0 ± 93.0 (24) 216.0 (MΩ) Data Table
Neocortex pyramidal cell layer 5-6 Auditory cortex layer 5 corticothalamic pyramidal neurons input resistance (MΩ) 125.0 ± 41.0 (47) 125.0 (MΩ) Data Table
Neocortex pyramidal cell layer 5-6 Auditory cortex layer 5 corticothalamic pyramidal neurons membrane time constant (ms) 17.0 ± 16.5 (47) 17.0 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Auditory cortex layer 6 corticothalamic regular firing pyramidal neurons membrane time constant (ms) 14.6 ± 5.6 (24) 14.6 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Auditory cortex layer 5 corticothalamic pyramidal neurons resting membrane potential (mV) 60.6 ± 6.1 (47) -60.6 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Auditory cortex layer 6 corticothalamic regular firing pyramidal neurons resting membrane potential (mV) 63.9 ± 7.0 (24) -63.9 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Auditory cortex layer 5 regular firing corticothalamic pyramidal neurons ADP amplitude (mV) 0.84 ± 1.1 0.84 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Auditory cortex layer 5 regular firing corticothalamic pyramidal neurons fast AHP amplitude (mV) 2.7 ± 2.9 2.7 (mV) Data Table
Neocortex pyramidal cell layer 5-6 Auditory cortex layer 5 regular firing corticothalamic pyramidal neurons input resistance (MΩ) 176.0 ± 87.0 176.0 (MΩ) Data Table
Neocortex pyramidal cell layer 5-6 Auditory cortex layer 5 regular firing corticothalamic pyramidal neurons membrane time constant (ms) 28.4 ± 12.8 28.4 (ms) Data Table
Neocortex pyramidal cell layer 5-6 Auditory cortex layer 5 regular firing corticothalamic pyramidal neurons resting membrane potential (mV) 63.3 ± 7.3 -63.3 (mV) Data Table

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Metadata values

Experimental condition Value
Species Mice
ElectrodeType Patch-clamp
Strain Mice, Inbred BALB C
RecTemp 30.0 - 34.0
PrepType in vitro
ExternalSolution 5.0
external_1_pH 7.4
external_1_Mg 3.0
external_1_Ca 1.0
external_1_Na 153.25
external_1_Cl 136.5
external_1_K 2.5
external_2_pH 7.4
external_2_Mg 1.0
external_2_Ca 3.0
external_2_Na 153.25
external_2_Cl 136.5
external_2_K 2.5
InternalSolution 5.0
JxnPotential Unreported
AnimalAge 22.0 - 30.0
internal_0_pH 7.3
internal_0_Mg 1.0
internal_0_Na 2.4
internal_0_K 130.0
internal_0_GTP 0.4
internal_0_ATP 2.0
internal_0_Cl 15.14
internal_0_Ca 0.07
external_0_pH 7.4
external_0_Mg 1.0
external_0_Na 153.25
external_0_K 2.5
external_0_Cl 136.5
external_0_Ca 3.0
external_0_glucose 10.0

Data table listing

Data Table Article Title Authors Journal Year Table needs expert? Ephys table mentions Curated by Times validated
36123 Differences in intrinsic properties and local network connectivity of identified layer 5 and layer 6 adult mouse auditory corticothalamic neurons support a dual corticothalamic projection hypothesis. Llano DA; Sherman SM Cereb. Cortex 2009 False 7 Shreejoy Tripathy, Nathalie Binnion, Brenna Li, 5
36124 Differences in intrinsic properties and local network connectivity of identified layer 5 and layer 6 adult mouse auditory corticothalamic neurons support a dual corticothalamic projection hypothesis. Llano DA; Sherman SM Cereb. Cortex 2009 False 5 Shreejoy Tripathy, Nathalie Binnion, Brenna Li, 3