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Article: Increased excitatory synaptic input to granule cells from hilar and CA3 regions in a rat model of temporal lobe epilepsy.

Full Text (publisher's website) ; Article Metadata ; Article Data (extracted)
Zhang W; Huguenard JR; Buckmaster PS
J. Neurosci., 2012


Table 1.

Intrinsic electrophysiological properties of normotopic granule cells in control and epileptic rats

Control Epileptic
n (cells) 32 37
Resting membrane potential (mV) −71 ± 1 −71 ± 1
Input resistance (MΩ) 310 ± 19 272 ± 15
Membrane time constant (ms) 22 ± 2 25 ± 1
Action potential threshold (mV) −32 ± 1 −34 ± 1
Action potential amplitude (mV) 125 ± 2 125 ± 2
Action potential frequency (Hz at 200 pA) 18 ± 2 19 ± 1
  • Values indicate mean ± SEM. There were no statistically significant differences.


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Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Dentate gyrus granule cell membrane time constant (ms) 22.0 ± 2.0 22.0 (ms) Data Table
Dentate gyrus granule cell spike threshold (mV) -32.0 ± 1.0 -32.0 (mV) Data Table
Dentate gyrus granule cell firing frequency 18.0 ± 2.0 18.0 (Hz) Data Table
Dentate gyrus granule cell resting membrane potential (mV) -71.0 ± 1.0 -71.0 (mV) Data Table
Dentate gyrus granule cell input resistance (MΩ) 310.0 ± 19.0 310.0 (MΩ) Data Table