|
Article: Alterations in intrinsic membrane properties and the axon initial segment in a mouse model of Angelman syndrome.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Kaphzan H; Buffington SA; Jung JI; Rasband MN; Klann E J. Neurosci., 2011
Table 1.
Passive intrinsic properties of CA1 pyramidal cells
| Parameter | WT | AS | p value |
|---|---|---|---|
| Resting potential (mV) | −61.7 (±1.5) | −66.4 (±1.5) | <0.05 |
| Time constant | 29.2 (1.9) | 29.0 (2.0) | ns |
| Input resistance (MΩ) | 237.8 (13.2) | 239.8 (13.1) | ns |
-
Altered passive intrinsic properties in hippocampal CA1 pyramidal neurons from AS model mice and their wild-type littermates. Resting potential is significantly more hyperpolarized in AS mice (WT: n = 15 cells, 5 mice; AS: n = 15 cells, 5 mice).
Inferred neuron-electrophysiology data values
| Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
|---|---|---|---|---|---|
| Hippocampus CA1 pyramidal cell | input resistance | 237.8 | 237.8 (MΩ) | Data Table | |
| Hippocampus CA1 pyramidal cell | resting membrane potential (mV) | -61.7 ± 1.5 | -61.7 (mV) | Data Table | |
| Hippocampus CA1 pyramidal cell | membrane time constant | 29.2 | 29.2 (ms) | Data Table |