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Article: Activity of ventral medial thalamic neurons during absence seizures and modulation of cortical paroxysms by the nigrothalamic pathway.

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Paz JT; Chavez M; Saillet S; Deniau JM; Charpier S
J. Neurosci., 2007


Table 1.

Comparison of membrane properties of VM thalamic neurons in GAERS and nonepileptic Wistar rats

Vm (mV) Rin (MΩ) τ (ms) AP threshold (mV) AP amplitude (mV) AP duration (ms)
Control −58.9 ± 1.1 (9) 22.9 ± 2.1 (8) 12.2 ± 1.1 (8) −49.3 ± 0.5 (9) 47.1 ± 1.9 (9) 1.18 ± 0.06 (9)
GAERS −60.3 ± 1.1 (14) 25.2 ± 1.3 (12) 17.8 ± 2.7 (12) −50.8 ± 0.4 (14) 46.3 ± 1.8 (14) 1.19 ± 0.05 (14)
  • The electrical membrane properties of VM thalamic neurons recorded from GAERS and nonepileptic Wistar rats did not differ significantly (p > 0.05 for all parameters, t test). The number of cells for each parameter is indicated in parentheses. AP, Action potential; R in, membrane input resistance; τ, membrane time constant; V m, interictal mean membrane potential.


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Inferred neuron-electrophysiology data values

Neuron Type Neuron Description Ephys Prop Extracted Value Standardized Value Content Source
Thalamus relay cell Ventral Medial Thalamic Nucleus Neuron resting membrane potential (mV) -58.9 ± 1.1 (9) -58.9 (mV) Data Table
Thalamus relay cell Ventral Medial Thalamic Nucleus Neuron input resistance (MΩ) 22.9 ± 2.1 (8) 22.9 (MΩ) Data Table
Thalamus relay cell Ventral Medial Thalamic Nucleus Neuron membrane time constant (ms) 12.2 ± 1.1 (8) 12.2 (ms) Data Table
Thalamus relay cell Ventral Medial Thalamic Nucleus Neuron spike threshold (mV) -49.3 ± 0.5 (9) -49.3 (mV) Data Table
Thalamus relay cell Ventral Medial Thalamic Nucleus Neuron spike amplitude (mV) 47.1 ± 1.9 (9) 47.1 (mV) Data Table
Thalamus relay cell Ventral Medial Thalamic Nucleus Neuron spike half-width (ms) 1.18 ± 0.06 (9) 1.18 (ms) Data Table